Kiyoshi Migita Selected Research

Familial Mediterranean Fever (Periodic Disease)

1/2022	Total Hip Joint Replacement in a Patient with Colchicine-Resistant Familial Mediterranean Fever under Canakinumab Treatment.
10/2021	Granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α in combination is a useful diagnostic biomarker to distinguish familial Mediterranean fever from sepsis.
10/2021	Immunoglobulin A Vasculitis in a Japanese Patient with Complete Familial Mediterranean Fever Carrying MEFV Exon 10 Mutation.
12/2020	Familial Mediterranean fever phenotype progression into anti-cyclic citrullinated peptide antibody-positive rheumatoid arthritis:a case report.
9/2020	Next-generation sequencing of the whole MEFV gene in Japanese patients with familial Mediterranean fever: a case-control association study.
9/2020	The possession of exon 2 or exon 3 variants in the MEFV gene promotes inflammasome activation in Japanese patients with familial Mediterranean fever with a heterozygous exon 10 mutation.
11/2019	Canakinumab eliminates resistant familial Mediterranean fever in a Japanese girl.
9/2018	Subclinical inflammation in a case of menstruation-induced familial Mediterranean fever: A case report.
1/2018	MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway.
11/2017	Tocilizumab is effective in a familial Mediterranean fever patient complicated with histologically proven recurrent fasciitis and myositis.

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Kiyoshi Migita Research Topics

Disease

46	Rheumatoid Arthritis 01/2022 - 02/2004
19	Familial Mediterranean Fever (Periodic Disease) 01/2022 - 05/2013
18	Autoimmune Diseases (Autoimmune Disease) 06/2022 - 12/2003
18	Fever (Fevers) 06/2021 - 06/2012
16	Infections 12/2021 - 04/2005
14	Inflammation (Inflammations) 01/2021 - 02/2004
14	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 05/2020 - 03/2005
11	Adult-Onset Still's Disease 01/2022 - 01/2015
10	Autoimmune Hepatitis 01/2021 - 07/2007
9	Arthritis (Polyarthritis) 12/2021 - 01/2008
9	Fibrosis (Cirrhosis) 01/2020 - 04/2006
8	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 01/2012
8	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2020 - 03/2007
8	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 01/2006
8	Liver Diseases (Liver Disease) 11/2019 - 01/2006
7	Takayasu Arteritis (Arteritis, Takayasu's) 04/2022 - 01/2014
7	Disease Progression 01/2022 - 01/2007
7	Thrombocytopenia (Thrombopenia) 01/2020 - 04/2009
6	Immunoglobulin G4-Related Disease 01/2022 - 01/2012
6	Rheumatic Diseases (Rheumatism) 12/2021 - 06/2015
6	Hepatitis 11/2019 - 04/2006
6	Hepatocellular Carcinoma (Hepatoma) 01/2011 - 05/2002
5	Myositis (Idiopathic Inflammatory Myopathies) 04/2022 - 01/2011
5	Lupus Nephritis 01/2022 - 01/2014
5	Liver Failure 01/2022 - 03/2005
5	Edema (Dropsy) 01/2020 - 01/2015
5	Venous Thrombosis (Deep-Vein Thrombosis) 07/2018 - 04/2009
5	Venous Thromboembolism 04/2018 - 01/2011
4	Systemic Scleroderma (Systemic Sclerosis) 11/2020 - 01/2016
4	Melanoma (Melanoma, Malignant) 05/2019 - 06/2008
4	Osteoarthritis 04/2018 - 02/2004
4	Jaundice (Icterus) 01/2018 - 01/2007
4	Hepatitis B 03/2016 - 04/2005
3	Neoplasms (Cancer) 04/2022 - 05/2002
3	Dermatomyositis (Dermatopolymyositis) 04/2022 - 01/2011
3	Pancytopenia 01/2022 - 01/2016
3	Mixed Connective Tissue Disease (MCTD) 01/2022 - 08/2019
3	Ascites 12/2021 - 07/2018
3	Vasculitis (Vasculitides) 12/2021 - 01/2010
3	Sepsis (Septicemia) 10/2021 - 01/2018
3	Central Nervous System Lupus Vasculitis 04/2020 - 01/2017
3	Ulcer 11/2019 - 01/2014
3	Genetic Predisposition to Disease (Genetic Predisposition) 09/2019 - 08/2006

Drug/Important Bio-Agent (IBA)

22	AntibodiesIBA 04/2022 - 09/2003
19	CytokinesIBA 10/2021 - 02/2004
17	SteroidsIBA 06/2022 - 09/2006
14	Colchicine FDA LinkGeneric 01/2022 - 01/2014
12	AutoantibodiesIBA 04/2022 - 12/2003
12	HLA-DRB1 Chains (HLA DRB1)IBA 01/2022 - 11/2006
12	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 01/2005
10	tocilizumab (atlizumab)FDA Link 04/2022 - 08/2011
10	Biomarkers (Surrogate Marker)IBA 10/2021 - 09/2011
10	Interleukin-6 (Interleukin 6)IBA 06/2021 - 04/2005
10	Methotrexate (Mexate)FDA LinkGeneric 12/2020 - 01/2008
9	Tacrolimus (Prograf)FDA LinkGeneric 01/2022 - 04/2006
9	Immunoglobulin G (IgG)IBA 01/2022 - 01/2011
8	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 08/2006
7	GlucocorticoidsIBA 04/2022 - 08/2011
7	Prednisolone (Predate)FDA LinkGeneric 01/2022 - 06/2012
7	Serum Amyloid A Protein (Serum Amyloid A)IBA 03/2021 - 05/2002
7	InflammasomesIBA 01/2021 - 01/2014
6	Cyclosporine (Ciclosporin)FDA LinkGeneric 06/2022 - 01/2011
6	C-Reactive ProteinIBA 03/2021 - 01/2015
6	Interleukin-18 (Interleukin 18)IBA 09/2020 - 02/2004
5	Immunoglobulins (Immunoglobulin)IBA 06/2022 - 01/2017
5	EnzymesIBA 04/2022 - 12/2003
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2015
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2021 - 01/2002
5	PyrinIBA 12/2020 - 01/2008
5	HLA Antigens (Human Leukocyte Antigens)IBA 11/2019 - 01/2012
5	Alanine Transaminase (SGPT)IBA 08/2019 - 01/2011
5	Heparin (Liquaemin)FDA LinkGeneric 04/2018 - 04/2009
5	AA amyloidosisIBA 05/2017 - 05/2002
4	Anti-Citrullinated Protein AntibodiesIBA 01/2022 - 01/2020
4	Methylprednisolone FDA LinkGeneric 12/2021 - 01/2015
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2021 - 01/2015
4	Pharmaceutical PreparationsIBA 08/2021 - 01/2014
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 01/2005
4	BilirubinIBA 08/2019 - 01/2006
4	Amyloid (Amyloid Fibrils)IBA 12/2018 - 11/2006
4	Polysaccharides (Glycans)IBA 01/2018 - 06/2015
3	Immunoglobulin A (IgA)IBA 01/2022 - 10/2021
3	Rheumatoid FactorIBA 01/2022 - 08/2011
3	canakinumab FDA Link 01/2022 - 11/2019
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2022 - 01/2015
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 10/2021 - 01/2019
3	Interleukin-17 (Interleukin 17)IBA 10/2021 - 12/2016
3	LigandsIBA 01/2021 - 02/2010
3	Uric Acid (Urate)IBA 01/2021 - 05/2014
3	InterferonsIBA 01/2020 - 01/2011
3	ChemokinesIBA 01/2020 - 12/2018
3	InterleukinsIBA 01/2020 - 01/2014
3	Carrier Proteins (Binding Protein)IBA 01/2020 - 12/2018
3	Hepatitis B Surface Antigens (HBsAg)FDA Link 11/2019 - 12/2012
3	ImmunosorbentsIBA 05/2019 - 12/2003
3	Serum AlbuminIBA 07/2018 - 10/2010

Therapy/Procedure

29	Therapeutics 04/2022 - 01/2005
6	Knee Replacement Arthroplasty (Total Knee Replacement) 05/2017 - 04/2009
4	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2022 - 04/2009
3	Liver Transplantation 01/2022 - 01/2007